Turmeric is a yellow spice from India, with multiple health properties. However, it is well known that Turmeric and its main asset, Curcumin, have a low bioavailability, that is they are difficult to absorb from our body and for this reason little usable. For this reason, the International Biolife have thought to use in our product “BIOLIFE CURCUMIN PLUS”, a highly bioavailable and more soluble turmeric extract. As shown by clinical studies in vitro and in vivo, our Turmeric extract is 39 times more bioavailable than a common dry extract of Turmeric titrated, and 99 times more hydrodispersible in water and 20% more dispersible in a ringer solution, a isotonic solution with blood. In addition, the 35% curcuminoid titration, by high-performance liquid chromatography (HPLC), ensures the effective presence of assets (Curcumin, Demetossicurcumin, bis-demetossicurcumin) and their anti-oxidants and anti-inflammatory actions. To support such activities, we have associated a second extract able to increase and supportthe anti-infiammatory action of turmeric: an extract of broccoli titrated in sulforaphane to 0.3%. Sulforaphone is a molecule belonging to the family of isothyocytes, an important natural inducer of phase 2 enzymes, the most important detoxifying enzymes of our body, able to eliminate substances harmful to our health, pollutants and free radicals. Curcuminoids in synergy with sulforaphane interrupt the cascade of pro-inflammatory signals and increase endogenous antioxidant levels much more than individual phytocomplexes. Clinical and preclinical evidence indicates that chronic degenerative conditions are better addressed by multi-target therapy rather than mono-target therapy, and that therapeutic agents capable of modulating multiple cellular targets, such as Curcumin and Sulphoraphane, have great therapeutic potential in the treatment complementary to the multiple chronic inflammatory diseases.
Why recommend BIOLIFE CURCUMIN PLUS
Bioavailability of phytocomplexes is central to the evaluation of the potential of an extract and its selection. In fact, the action of a compound is directly proportional to the percentage that can reach the plasma circulation, before being metabolized and eliminated.The limit of the Turmeric extracts present on the market is linked to the low bioavailability of Curcumin, which, being quickly metabolized and eliminated, cannot carry out its activities. To obviate this, it is conjugated with other spices (for example the piperin) to improve its absorption, but it is not always well tolerated. Our Turmeric extract, however, is more bioavailable. As demonstrated by a recent in vivo clinical trial, the extract contained in BIOLIFE CURCUMIN PLUS shows a higher plasma concentration of Curcumin compared to subjects in which a common curcumin extract has been administered.
Main mechanisms of action of curcuminoids:
- Antioxidant: Ros Scavenger, very useful for the prevention of degenerative and cancer diseases.
- Lipid peroxidation inhibition and LDL oxidation, very useful in low-calorie diets for weight control.
- Cell cycle control and modulation by facilitating promoting in tumor cell lines (NF-&B, AP-1; STAT3; Egr-1; PPAR’ ; Chain-1; Inhibition of oprmetalloteinase “MMPs 9”.
- Anti-inflammatory action: interferes on the two main pro-inflammatory tracks COX and LOX.
Benefits of BIOLIFE CURCUMIN PLUS
Primary prevention in neuro-degenerative diseases. Adjuvant in cancer therapies. Liver and joint support.
Aid in low-calorie regimens to reduce plateau in low-calorie diets. This phenomenon occurs during a low-calorie diet, and in which the patient follows the diet program perfectly, but nevertheless does not lose MASSA GRASSA. At this time integration is advisable to avoid the patient is disappointed and interrupt the food pathway.
CURIOSITY: Since ancient times, India has been the world’s largest consumption of tumeric, it is not by change one of the countries with the lowest incidence of cancer in the world!
IMPORTANT: To achieve effective results and stay healthy, turmeric supplements must be associated with a healthy lifestyle, a proper and balanced diet and physical activity.
DOSAGE: 10 ml per day is recommended before the main meal
INDICATIONS: Food supplement based on Curcumin and Sulforafano.
CONTENT OF ACTIVE SUVSTANCES (in 10 ml of product):
– Turmeric dry extract 250 mg (of which Curcuminoids 87.5 mg)
– Broccoli dry extract 100 mg (of which Sulforaphane 0.3 mg)
WARNING: Supplements are not intended as substitutes for a varied and balanced diet and a healthy lifestyle. Do not exceed the recommended dose. Keep out of reach of children under 3 years. Store in a cool and dry place. Do not take during pregnancy, breastfeeding, ulcer, obstruction of the bile duct and/or gallstones. Check PT – INR in coumarin patients according to your health care provider. Gastric disorders may occur in sensitive subjects, despite the protective gastro effect, sometimes diarrhea. Do not use in case of thyroid dysfunction (additional warning for broccoli extract (Brassica oleracea L.)) from Exhibit 1 to DM 10 August 2018 on the regulation of use in food supplements of does not contain allergens (Annex III encore of the 2007/68/CE Directive).
STORAGE: Store in well-closed containers, protected from light, heat and humidity.